Remembering 6 Female-Hosted Daytime Talk Show Disasters

2. The Megan Mullally Show [2006]

Number of Episodes: 71

Premiering only four months after the series finale of Will & Grace aired, TBS confused viewers by promoting its daytime syndicated talk show with teasers featuring both Mullally and her Will & Grace character Karen. When audiences realized that Mullally was nothing in real life like Karen Walker, ratings fell to dismal numbers and Fox News labeled the program one of the "worst talk shows in TV history" by Fox News.

Highlights: Frequent chats with Will & Grace alum Sean Hayes and any segment involving Neil Patrick Harris (see his Les Mis duet with Jason Segel below).

Lowlights: Sexually charged tickle fights with Sex and the City star Chris Noth.

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