Caveat: Both House of Payne and Perry's other current series, Meet the Browns, are extensions of the Madea universe. But said universe has spawned countless side characters related and distantly related to Perry's famous be-wigged, take no prisoners matriarch that any number of fictional folks from the TP empire could potentially spawn their own television comedy spin-offs. (With the exception of For Colored Girls, which would probably not make the best sitcom.)
May we suggest something along the lines of Tyler Perry's Madea's Perfect Strangers, in which Madea gets an unexpected long term house guest played by Bronson Pinchot (of the Eastern Mediterranean branch of the family)? Or Tyler Perry's All in the Family, focusing on politically incorrect Uncle Joe, the Archie Bunker of the Perryverse?
Need inspiration? Review Perry's greatest hits in Movieline's Tyler Perry Box Office Paradox investigation and chime in with your best proposed Tyler Perry sitcom ideas below.
ยท House of Payne cancelled; TBS orders new Tyler Perry comedy series based on movie [EW]